Skip to main content
. 2022 Mar 15;23(6):3175. doi: 10.3390/ijms23063175

Figure 3.

Figure 3

Functional evaluation of elexacaftor-based combinations on nasal epithelia derived from the TT190 patient (L467F-F508del/E585X). (A) Representative short-circuit current recordings on epithelia derived from patient’s nasal cells treated for 24 h with vehicle alone (DMSO) or Elexa (3 µM), or Elexa/Teza (3 µM/10 µM) or ETI (3 µM/10 µM/5 µM). (B) Scatter dot plot showing the summary of results obtained from experiments described in (A). Data reported are the amplitude of the current blocked by 20 µM inh-172 (ΔIscinh-172).