Table 2.
Selected top 25 plasma metabolites.
| Metabolites | Category | t-Statistics | FDR |
|---|---|---|---|
| Daidzein 4′-sulfate | Xenobiotics | −20.13 | 0.0000017 |
| PE 38:4 | Phospholipids | −9.516 | 0.0008065 |
| PE 38:4 Isomer B | Phospholipids | −9.074 | 0.0008065 |
| PE P-34:2 or PE O-34:3 | Phospholipids | 9.062 | 0.0008065 |
| 3-Methylhistidine | Amino acids | 8.455 | 0.0011983 |
| PC P-36:5 or PC O-36:6 | Phospholipids | 7.758 | 0.0019206 |
| PE O-37:5 (PE O-17:1_20:4) | Phospholipids | 7.614 | 0.0019206 |
| N-α-Acetyl-L-ornithine | Amino acids | −7.491 | 0.0019206 |
| N-Methylhistidine | Amino acids | 7.491 | 0.0019206 |
| PE P-36:4 or PE O-36:5 | Phospholipids | 7.025 | 0.0029885 |
| PC P-38:6 or PC O-38:7 | Phospholipids | 6.740 | 0.0037446 |
| PE O-38:6 (PE O-18:1_20:5) | Phospholipids | 6.637 | 0.0037446 |
| PE 36:4 | Phospholipids | −6.628 | 0.0037446 |
| 3-Aminotyrosine | Amino acids | −6.466 | 0.0042649 |
| PE 38:5 (PE 16:0_22:5) | Phospholipids | −6.387 | 0.0044006 |
| (2R)-3-Hydroxyisovaleroylcarnitine | Amino acids | 6.173 | 0.0053753 |
| PE 36:1 (PE 18:0_18:1) | Phospholipids | −6.137 | 0.0053753 |
| PE P-38:3 or PE O-38:4 | Phospholipids | 6.035 | 0.0057137 |
| PC O-36:3 | Phospholipids | 6.007 | 0.0057137 |
| PE P-38:6 or PE O-38:7 | Phospholipids | 5.747 | 0.0075186 |
| PC P-34:1 or PC O-34:2 | Phospholipids | 5.729 | 0.0075186 |
| PC 40:5 Isomer B | Phospholipids | −5.601 | 0.0085627 |
| (3-Carboxypropyl)trimethylammonium | Xenobiotics | 5.550 | 0.0088038 |
| PC P-34:1 or PC O-34:2 Isomer A | Phospholipids | 5.479 | 0.0093114 |
| PC O-37:5 | Phospholipids | 5.394 | 0.0100850 |
The top 25 metabolites are presented. Benjamini & Hochberg procedure was used to adjust for multiple comparisons, and statistical significance was defined as FDR < 0.05. PC, phosphatidylcholine; PE, phosphatidylethanolamine.