Table 4.
Previous studies about HRV and patient outcomes in COPD.
| Selected Studies | Age (Years) |
FEV1 (%) | SDNN (ms) | HF (nu) | HF/LF | Principal Outcomes |
|---|---|---|---|---|---|---|
| Bédard, et al. (n = 41) |
67 | 45 | NA | NA | 1.9 | HRV correlated with disease severity and did not seem to be influenced by anticholinergic or adrenergic medications. |
| Camillo, et al. (n = 31) |
66 | 46 | 33 | 55 | NA | HRV was not related to disease severity but mainly to the level of physical activity in daily life. |
| Bartels, et al. (n = 53) |
61 | 35 | NA | NA | 3.1 | The balance of sympathetic to parasympathetic cardiac modulation decreased in patients with COPD during maximal volitional exercise. |
| Camillo, et al. (n = 20) |
67 | 40 | 29 | 56 | 0.9 | High-intensity exercise training improved HRV at rest and during orthostatic stimulus in patients with COPD. |
| Ricci-Vitor, et al. (n = 13) |
67 | 48.3 | 17 | NA | NA | The exclusive resistance training improved sympathetic and parasympathetic components of autonomic nervous system representing by SDNN, LF, and HF. |
| Zupanic, et al. (n = 31) |
61 | NA | 24 | 45 | 1.8 | A 4-week rehabilitation improved HRV (SDNN). |
| Leite et al. (n = 37) |
63 | 46 | 20 | 37 | 1.7 | HRV indexes at rest was correlated with aerobic physiological variables obtained at a maximal exercise test. |
| Goulart, et al. (n = 10) |
61 | 32 | NA | 54 | 0.9 | COPD patients with impaired respiratory muscle strength showed marked sympathetic modulation and a reduced parasympathetic response; reduced HRV complexity was observed during a respiratory sinus arrhythmia maneuver. |
COPD = chronic obstructive pulmonary disease; FEV1 = forced expiratory volume in one second; SDNN = standard deviation of N-N interval; HF = high frequency; LF = low frequency; HRV = heart rate variability.