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. 2022 Mar 21;15(3):385. doi: 10.3390/ph15030385

Table 2.

Cytotoxicity of examined compounds towards HaCaT cell line, represented as IC50 (compound concentration that inhibited 50% of the cell growth) in mg/mL.

Polyphenol IC50 (mg/mL)
Hesperetin >1
Hesperidin >1
Naringenin 0.528 ± 0.047
Naringin >1
Taxifolin 0.495 ± 0.047
Rutin >1
Isoquercitrin >1
Morin 0.347 ± 0.016
Chlorogenic acid 0.279 ± 0.008
Ferulic acid >1
p-coumaric acid >1
Gallic acid <0.080