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. 1999 Nov;43(11):2579–2585. doi: 10.1128/aac.43.11.2579

FIG. 5.

FIG. 5

Correlation between topoisomerase IC50 and MIC determined by using S. pneumoniae C3LN4 and its fluoroquinolone-resistant mutants. ●, topoisomerase IV (correlation = 0.97); ○, DNA gyrase (correlation = 0.57).