Table 3.
Drugs mixtures quantitative composition.
| Drug | Step 1: Drug Products Compatibility and Stability Study | Step 2: Stability Study in Clinical Use | ||||
|---|---|---|---|---|---|---|
| Initial Cc (µg mL−1) | Final Cc 2 Drugs Comb (µg mL−1) |
Final Cc 3 Drugs Comb (µg mL−1) |
Final Cc 4 Drugs Comb (µg mL−1) |
Final Cc 5 Drugs Comb (µg mL−1) |
Concentration after Dilution with NaCl 0.9% or G5% (µg mL−1) |
|
| Ketamine | 50,000 | 25,000 | 16,670 | 12,500 | 10,000 | 500 |
| Clonidine | 150 | 75 | 50 | 37.5 | 30 | 5 |
| Loxapine | 25,000 | 12,500 | 8330 | 6250 | 5000 | 500 |
| Midazolam | 5000 | 2500 | 1670 | 1250 | 1000 | 500 |
| Sufentanil | 5 | 2.5 | 1.67 | 1.25 | 1 | 1 |
Cc = Concentration; Comb = Combination.