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. 2022 Mar 19;10(3):479. doi: 10.3390/vaccines10030479

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Proportion of hospitalizations (A,B) and deaths (C,D) avoided by 10 million booster shots compared to a baseline scenario of no booster shots, depending on the targeted age groups and the level of transmission during the winter, over the period from 1 September 2021 to 1 March 2022. In all strategies, primary vaccination is stopped on 1 September 2021. The increase in transmission starts on 20 September 2021 and is relative to the mean transmission levels during the summer 2021 (Reff = 1.0). (A,C) Vaccine efficacy decreased only for people aged 65 years and older. (B,D) Vaccine efficacy decreased for all age groups.