TABLE 2.
Inferior regimen |
P value for the following superior regimen:
|
|||||||
---|---|---|---|---|---|---|---|---|
L-nystatina
|
L-amphotericin Ba
|
ABLCb
|
Amphotericin Ba
|
|||||
5 mg/kg | 1 mg/kgc | 5 mg/kg | 1 mg/kg | 5 mg/kg | 1 mg/kg | 5 mg/kg | 1 mg/kgc | |
L-nystatin, 1 mg/kgac | 0.035 | 0.0004 | 0.024 | 0.56 | ||||
L-amphotericin, 5 mg/kga | 0.24 | |||||||
L-amphotericin, 1 mg/kga | <0.0001 | 0.032 | 0.005 | 0.017 | 0.49 | 0.002 | 0.072 | |
ABLC, 5 mg/kgb | 0.014 | 0.2 | 0.72 | |||||
ABLC, 1 mg/kgb | <0.0001 | 0.15 | 0.0006 | 0.044 | 0.005 | 0.24 | ||
Amphotericin B, 5 mg/kga | 0.008 | 0.23 | ||||||
Amphotericin B, 1 mg/kgac | 0.03 | 0.95 | 0.0003 | 0.15 | 0.51 | |||
Liposomes and dextrose | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
Given on days 1, 2, 4, and 7.
Seven doses given on days 1 to 7.
Data are for only a single experiment.