TABLE 3.

Survival and colony geometric mean counts for mice infected with A. fumigatus AF65 and treated with all drugs at 5 and 1 mg/kg daily^a

Group	No. of infected mice	No. (%) of mice that survived	Colony counts/organ
			Liver	Kidney
L-nystatin, 5 mg/kg (days 1, 2, 4, and 7)	20	18 (90)	1b	<1c
L-nystatin, 1 mg/kg (days 1, 2, 4, and 7)	10	5 (50)	35	63
L-amphotericin, 5 mg/kg (days 1, 2, 4, and 7)	20	14 (70)	7	15
L-amphotericin, 1 mg/kg (days 1, 2, 4, and 7)	20	4 (20)	72	211
ABLC, 5 mg/kg (days 1 to 7)	20	10 (50)	19	22
ABLC, 1 mg/kg (days 1 to 7)	20	3 (15)	114	245
Amphotericin B, 5 mg/kg (days 1, 2, 4, and 7)	20	11 (55)	14	13
Amphotericin B, 1 mg/kg (days 1, 2, 4, and 7)	10	5 (50)	54	68
Controlsd	70	0 (0)

^aResults are for data pooled from all experiments (except the pilot experiment). 

^bP = 0.0032 for L-nystatin at 5 mg/kg versus all doses of all drugs. 

^cP = <0.0001 for L-nystatin at 5 mg/kg versus all doses of all drugs. 

^dFive percent dextrose or empty liposomes.