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. 2022 Mar 25;13:128. doi: 10.1186/s13287-022-02805-3

Fig. 5.

Fig. 5

Differences in the antifibrotic effects of subcapsular and parenchymal MSC transplantation in AKI-CKD mice at 28 days. A Experimental design. B Serum creatinine levels in the groups at 28 days after IRI. ***p < 0.001, ANOVA corrected with the Bonferroni coefficient. n = 4–5 mice per group. C Quantitative assessment of fibrotic areas. **p < 0.01; *p < 0.05, ANOVA corrected with the Bonferroni coefficient. n = 4–5 mice per group. D Representative micrographs showing Masson staining of renal collagen deposition at 28 days after IRI in the various groups as indicated. E Representative micrographs showing PAS staining in the various groups. F Representative immunohistochemical staining of fibronectin in the groups after 28 days of IRI. G Quantitative analysis of the fibronectin-positive areas in the groups after IRI. ***p < 0.001, ANOVA corrected with the Bonferroni coefficient. n = 4–5 per group