Table 2.
Identifying protective HLA alleles in different autoimmune diseases.
| Disease | Protective HLA Class II Allele | References |
|---|---|---|
| Graves’ disease | HLA-DRB1*07 | [54] |
| HLA-DQB1*02 | ||
| HLA-DQA1*02 | ||
| Hashimoto’s thyroiditis | HLA-DRB1*07 | [55] |
| HLA-DQB1*02 | ||
| HLA-DQA1*02 | ||
| Rheumatoid arthritis | HLA-DRB1*0103 | [56] |
| HLA-DRB1*07 | ||
| HLA-DRB1*1201 | ||
| HLA-DRB1*1301 | ||
| HLA-DRB1*1501 | ||
| Multiple sclerosis | DRB1*14-DQB1*06-DQA1*0102 | [9] |
| Type 1 diabetes | DRB1*14-DQB1*06-DQA1*0102 | [57] |
| DRB1*15-DQB1*06-DQA1*01 | ||
| Systemic lupus erythematosus | DR4 | [58] |
| DR5 | ||
| DR11 | ||
| DR14 |