Table 17.

Homology of predicted peptides binding to HLA alleles to bacterial proteins.

Allele	SjS Protein	Core Sequence	Bacteria	Bacterial Protein	Homology
HLA -DRB1*04:05	Ro52	EAGMVSFYN	Legionella moravica	Ankyrin	88.9%
			Legionella sp. Km535	Ankyrin repeat domain-containing protein	88.9%
	Ro52	MVSFYNITD	Legionella moravica	Ankyrin	88.9%
			Legionella sp. Km535	Ankyrin repeat domain-containing protein	88.9%
HLA-DRB4*01:01	Ro60	TYYIKEQKL	Helicobacter sp. 11S03491-1	Protoporphyrinogen oxidase	100%
			Fusobacterium	Uncharacterized	100%
			Fusobacterium	Uncharacterized	100%
HLA-DRB3*01:01	La	CREDLHILF	Virgibacillus massiliensis	Uncharacterized	100%
HLA-DRB4*01:01	M3R	LVTIIGNIL	Uncultured	Uncharacterized	88.9%
HLA-DRB1*01:01	Alpha Fodrin	IKLLQAQKL	Eubacteriaceae	Glycosyltransferase	100.0%
			Candidatus Pseudoramibacter	Glycosyltransferase	100.0%
HLA- DRB1*15:01	Alpha Fodrin	EVLDRWRRL	Desulfonatronum sp.	Thioredoxin	88.9%
			Thermoleophilaceae bacterium	Proline RNA ligase	88.9%
			Thermoleophilaceae bacterium	Proline tRNA ligase	88.9%
			Nonomuraea nitratireducens	DUF885 family protein	88.9%
			Nonomuraea phyllanthi	DUF885 domain-containing protein	88.9%
			Firmicutes bacterium	Biotin protein ligase	88.9%
			Firmicutes bacterium	Biotin protein ligase	88.9%
			Streptomyces malaysiensis	Putative non-ribosomal peptide synthetase	100.0%
			Streptomyces malaysiensis	Non-ribosomal peptide synthetase	100.0%
			Streptomyces malaysiensis	Carrier domain-containing protein	100.0%
			Aquisphaera giovannonii	Phosphomannomutase/phosphoglucomutase	100.0%
			Streptomycetaceae bacterium	Uncharacterized protein	88.9%
			Curtobacterium sp. MCPF17_047	Uncharacterized protein	100.0%
			Nitriliruptorales bacterium	DUF1932 domain-containing protein	100.0%
			Paracoccus homiensis	Acetyltransferase (GNAT) family protein	100.0%
			Actinophytocola xanthii	SnoaL-like domain-containing protein	100.0%
			Frigoribacterium sp. PhB160	S-DNA-T family DNA segregation ATPase	100.0%
			Frigoribacterium sp. PhB107	S-DNA-T family DNA segregation ATPase	100.0%
			Frigoribacterium sp. ACAM 257	Cell division protein FtsK	100.0%
			Geodermatophilus sp. DF01_2	Peptidase_M16_C domain-containing protein	100.0%
			Acidobacteria bacterium	Uncharacterized protein	100.0%
			Nitrosococcus oceani C-27	Transposase	88.9%
			Nitrosococcus oceani (strain)	Y1_Tnp domain-containing protein	88.9%
			Dietzia sp. MeA6-2017	Uncharacterized protein	100.0%
			Firmicutes bacterium	Bifunctional ligase/repressor BirA	100.0%
			Dietzia sp. oral taxon 368	Uncharacterized protein	100.0%
			Saccharopolyspora sp. ASAGF58	Uncharacterized protein	100.0%
			Saccharopolyspora spinosa	Uncharacterized protein	100.0%
			Chloroflexi bacterium	Biotin [acetyl-CoA-carboxylase] ligase	100.0%
			Actinobacteria bacterium 13	Biotin [acetyl-CoA-carboxylase] ligase	100.0%
			Pelagibaca abyssi	Uncharacterized protein	100.0%
			Candidatus Kentron sp. LFY	Type III restriction enzyme	88.9%
			Planctomycetes bacterium	Diguanylate cyclase	88.9%
			Candidatus Kentron sp. LFY	Type III restriction enzyme, res subunit	88.9%
			Candidatus Solibacter sp.	3-isopropylmalate dehydratase large subunit	88.9%
			Hyalangium minutum	Uncharacterized protein	88.9%
			Actinokineospora terrae	AraC-type DNA-binding protein	88.9%
			Actinokineospora cianjurensis	AraC-like DNA-binding protein	88.9%
HLA-DRB4*01:01	Alpha Fodrin	IKLLQAQKL	Eubacteriaceae Candidatus Pseudoramibacter	Glycosyltransferase Glycosyltransferase	100.0% 100.0%