Table 7.
Other G4 ligands inducing topological switches.
| Ligand (Chemotype) |
Structure | Topology Switch | Refs. | ||
|---|---|---|---|---|---|
|
3,3-L2H2-6OTD (Oxazole-based) |
Figure 15 | ssDNA | ➔ | antiparallel (ion free) | [257] |
|
RHPS4 (acridinium) |
Figure 4 | hybrid | ➔ | antiparallel (in K+) | [282] |
| Berberine | Figure 13 | hybrid | ➔ | antiparallel (in K+) | [282] |
|
BRACO-19 (acridine) |
Figure 4 | hybrid | ➔ | antiparallel (in K+) | [282] |
| pyridostatin | Figure 6 | hybrid | ➔ | antiparallel (in K+) | [253] |
|
PhenDC3 (phenanthroline) |
Figure 6 | hybrid | ➔ | antiparallel (in K+) | [253,282] |
|
PDC-360A (pyridine-dicarboxamide) |
Figure 6 | hybrid | ➔ | antiparallel (in 10 mM K+) | [253] |
| hybrid | ➔ | parallel (in 60 mM K+) | [183] | ||
|
PDCd (pyridine-dicarboxamide) |
Figure 17 | hybrid | ➔ | antiparallel (in K+) | [183] |