Table 2.

Physical parameters for validation of final subunit vaccine constructs.

TLR4-Agonist
Model	GDT-HA	RMSD	MolProbity	Clash Score	Poor Rotamers	Rama Favoured
Initial	1	0	3.692	104.6	4.9	83.6
MODEL 1	0.9225	0.499	2.123	15.4	0.5	93.4
MODEL 2	0.9254	0.494	2.184	15.4	0.5	91.8
MODEL 3	0.9254	0.491	2.163	15.7	0.5	92.6
MODEL 4	0.9283	0.471	2.134	14.1	0.5	92.2
MODEL 5	0.9176	0.507	2.061	13.8	0.5	93.8
β-Defensin
Model	GDT-HA	RMSD	MolProbity	Clash Score	Poor Rotamers	Rama Favoured
Initial	1	0	3.707	101.6	5.1	82.7
MODEL 1	0.8978	0.55	2.164	17.9	0	93.8
MODEL 2	0.8995	0.54	2.153	16.7	0.9	93.4
MODEL 3	0.8952	0.559	2.169	18.1	0.4	93.8
MODEL 4	0.8918	0.557	2.164	17.9	0.9	93.8
MODEL 5	0.9012	0.545	2.18	17.9	0.4	93.4
50S Ribosomal Protein L7/L12
Model	GDT-HA	RMSD	MolProbity	Clash Score	Poor Rotamers	Rama Favoured
Initial	1	0	3.449	98.8	3.7	89.8
MODEL 1	0.9162	0.495	1.99	14.8	0.7	95.5
MODEL 2	0.9182	0.492	2.1	14.8	1.4	95.5
MODEL 3	0.9162	0.493	1.965	13.9	0.7	95.5
MODEL 4	0.9195	0.487	1.96	13.7	0.3	95.5
MODEL 5	0.9182	0.498	1.909	12	0.3	95.5

cla3.5 disulphide engineering of designed vaccine constructs.