TABLE 5.
Antimicrobial susceptibility of S. pneumoniae by specimen sourcea
| Antimicrobial agent | % Susceptibleb
|
|||
|---|---|---|---|---|
| Blood/CSFc (n = 370) | Respiratory tract (n = 682) | Ear (n = 85) | Eye (n = 58) | |
| Penicillin | 77.8 | 60.9d | 44.7d | 65.5d |
| Amoxicillin | 89.7 | 79.0d | 58.8d | 82.5 |
| Amoxicillin-clavulanate | 87.2 | 76.3d | 55.3d | 78.9 |
| Ceftriaxone | 88.4 | 79.9d | 60.0d | 84.2 |
| Erythromycin | 85.4 | 72.9d | 65.9d | 79.3 |
| Clindamycin | 96.5 | 93.8 | 88.2d | 87.9d |
| SXT | 92.7 | 86.6d | 77.4d | 93.0 |
| Tetracycline | 90.8 | 81.1d | 76.2d | 77.2d |
a
Of the 1,276 isolates, 81 were from specimen sources other than blood or cerebrospinal fluid, respiratory tract, ear, or eye and were thus excluded from this analysis.
b
Susceptible by using the interpretive categories recommended by NCCLS.
c
In addition to blood and cerebrospinal fluid (CSF), samples from other sterile sites may have been included.
d
The prevalence of susceptible strains was significantly lower (P < 0.05) than that for the blood or cerebrospinal fluid referent group.