Table 1.
Characteristics of MASALA participants qualifying for 10-year ASCVD risk assessment for statin allocation purposes.
| Overall | 10-year estimated ASCVD risk* |
|||||
|---|---|---|---|---|---|---|
| Low (<5%) |
Borderline (5-7.5%) |
Intermediate (7.5-20%) |
High (≥20%) |
p value | ||
| Number (%) | 660 (100) | 426 (64.6) | 72 (10.9) | 131 (19.9) | 31 (4.7) | |
| Age, years | 54 (48, 61) | 50 (45, 54) | 56 (53, 61) | 63 (60, 67) | 71 (68, 74) | <0.001 |
| Women | 360 (54.5) | 308 (72.3) | 18 (25.0) | 30 (22.9) | 4 (12.9) | <0.001 |
| Education ≥ Bachelor’s | 578 (87.6) | 371 (87.1) | 61 (84.7) | 119 (90.8) | 27 (87.1) | 0.589 |
| High family income* | 412 (64.5) | 288 (69.7) | 42 (60.0) | 69 (54.8) | 13 (43.3) | 0.006 |
| Abdominal obesity† | 523 (79.2) | 337 (79.1) | 58 (80.6) | 106 (80.9) | 22 (71.0) | 0.661 |
| Fasting glucose, mg/dL | 92 (86, 98) | 90 (85, 96) | 94 (89, 102) | 93 (89, 100) | 98 (90, 107) | <0.001 |
| HbA1c, % | 5.7 (5.5, 5.9) | 5.7 (5.5, 5.9) | 5.8 (5.5, 6.0) | 5.7 (5.5, 5.9) | 5.7 (5.5, 6.0) | 0.108 |
| Prediabetes‡ | 401 (60.8) | 241 (56.6) | 53 (73.6) | 82 (62.6) | 25 (80.7) | 0.004 |
| Total cholesterol, mg/dL | 196 (31) | 196 (30) | 196 (32) | 194 (32) | 197 (37) | 0.928 |
| HDL cholesterol, mg/dL | 49 (41, 59) | 52 (44, 62) | 43 (36, 50) | 44 (39, 54) | 45 (37, 55) | <0.001 |
| Triglycerides, mg/dL | 114 (87, 151) | 110 (83, 144) | 137 (102, 173) | 119 (89, 158) | 114 (83, 155) | <0.001 |
| Systolic blood pressure, mmHg | 124 (16) | 120 (14) | 126 (14) | 133 (16) | 142 (16) | <0.001 |
| Diastolic blood pressure, mmHg | 74 (10) | 72 (10) | 76 (11) | 78 (10) | 79 (11) | <0.001 |
| Hypertension medication use | 125 (18.9) | 44 (10.3) | 13 (18.1) | 49 (37.4) | 19 (61.3) | <0.001 |
| Current smoker | 21 (3.2) | 3 (0.7) | 5 (6.9) | 10 (7.6) | 3 (9.7) | <0.001 |
| Estimated 10-year ASCVD risk§ | 3.0 (1.3, 7.1) | 1.6 (1.0, 2.9) | 6.0 (5.4, 6.6) | 11.0 (9.0, 14.0) | 23.8 (21.1, 26.0) | <0.001 |
*
Family income ≥ 75,000 USD per year.
†
Waist circumference >80 cm for women or >90 cm for men.
‡
Glucose levels 100 – 125 mg/dL or HbA1c ≥5.7% and <6.5%.
§
Estimated using the Pooled Cohort Equations for non-Hispanic Whites.
Categorical variables are presented as number (%), and continuous variables are presented as mean (standard deviation) or median (interquartile range).
ASCVD = atherosclerotic cardiovascular disease events; HbA1c = glycosylated hemoglobin; HDL = high-density lipoprotein; MASALA = Mediators of Atherosclerosis in South Asians Living in America