External symptoms of shrimps with White tail disease (WTD). (A) MrNV-infected Penaeus vannamei showing signs of whitish muscle in the tail (arrows); (B) Cherax quadricarinatus showing signs of WTD with necrosis and myositis (arrows); (C,D) Clinical signs, whitish abdominal muscles (arrows), in the infected post-larvae of Penaeus indicus ((A) Reprinted from Aquaculture, Vol. 483, Jariyapong, P., Pudgerd, A., Weerachatyanukul, W., Hirono, I., Senapin, S., Dhar, A.K., Chotwiwatthanakun, C., Construction of an infectious Macrobrachium rosenbergii nodavirus from cDNA clones in Sf9 cells and improved recovery of viral RNA with AZT treatment, p. 9, Copyright (2018), with permission from Elsevier; (B) Reprinted from Aquaculture, Vol. 319 (1–2), Hayakijkosol, O., La Fauce, K., Owens, L., Experimental infection of redclaw crayfish (Cherax quadricarinatus) with Macrobrachium rosenbergii nodavirus, the aetiological agent of white tail disease, p. 5, Copyright (2011), with permission from Elsevier; (C,D) Reprinted from Aquaculture, Vol. 292(1–2), Ravi, M., Basha, A.N., Sarathi, M., Idalia, H.R., Widada, J.S., Bonami, J.R., Hameed, A.S., Studies on the occurrence of white tail disease (WTD) caused by MrNV and XSV in hatchery-reared post-larvae of Penaeus indicus and P. monodon, p. 4, Copyright (2009), with permission from Elsevier).