Figure 1.

Clinical response to isotretinoin therapy in a golden retriever dog with autosomal recessive congenital ichthyosis (ARCI). Pictures on the left were obtained before and those on the right after 3 months of treatment at the same body locations but on the contralateral sides. Picture before (a) and after treatment (b) on the trunk. Picture before (c) and after treatment (d), with clipped hair for better visualization of large white scales and latticelike hyperpigmentation (d). Picture before (e) and after treatment (f) in axillar region showing tan-to-yellow scales with variable hyperpigmentation.