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. 2022 Feb 26;10(3):370. doi: 10.3390/vaccines10030370

Table 4.

Results of conditional exact logistic regression analysis: risk of first- and second-dose AEFIs associated with Parkinson’s Disease and Multiple Sclerosis diagnosis. All estimates controlled for pairing factors (sex, age, comorbidities, allergies) and type of vaccine received (Gam-COVID-Vac or Pfizer-BioNTech).

Any AEFI Systemic AEFIs Local AEFIs
OR (95% CI) OR (95% CI) OR (95% CI)
First dose
Neurological diseases
No 1.00 1.00 1.00
Parkinson’s Disease 0.40 (0.11–1.19) 0.62 (0.16–2.12) 0.36 (0.09–1.20)
Multiple Sclerosis 0.41 (0.08–1.62) 1.30 (0.43–4.09) 0.42 (0.13–1.17)
Second dose
Neurological diseases
No 1.00 1.00 1.00
Parkinson’s Disease 0.19 * (0.03–0.66) 0.42 (0.12–1.29) 0.12 * (0.01–0.51)
Multiple Sclerosis 0.73 (0.15–3.42) 0.66 (0.20–2.05) 0.95 (0.28–3.17)

Notes: OR, odds ratio; CI, confidence interval. * statistically significant (p < 0.05).