Fig. 6.

C16-C1P rearrangement induced by CPTP α-6 helix during MD simulation (e.g., supplemental Video S2). C16-C1P is shown in stick representation with cyan hydrocarbon chains, red oxygen, blue nitrogen, and orange phosphate. A: View from beneath the bilayer interface (blue). CPTP residues are shown as space-filling. B: End-on view of α-6 helix aligned with the bilayer interface (blue line) showing the repositioning of C1P induced by interacting α-6 helix residues R156, W152, V153, and V154. C: Zoom view of C1P interacting with α-6 helix residues W152, R156, V154, and A161.