Fig. 10.
Pathway map detailing the biosynthesis and metabolism of the RORγ agonists 7α,26-diHC and 7β,26-diHC. Nonenzymatic oxidation is indicated by [O] on a pink background. 7α-HC, 7β-HC, and 7-OC have been found to be inverse agonists of RORγ.
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