Table 2.
Immunohistochemistry scoring for immune markers in both LCC defined subgroups.
| Marker | Pro-Immunogenic Tumors N = 11 | Pro-Tumorigenic Tumors N = 7 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Score | 0 | 1 | 2 | Positive (%) | Negative (%) | Avg. Score | 0 | 1 | 2 | Positive (%) | Negative (%) | Avg. Score |
| CD8 | 1 | 8 | 2 | 10 (90.91) | 1 (9.09) | 1.09 | 2 | 4 | 1 | 5 (71.43) | 2 (28.57) | 0.85 |
| CD4 | 8 | 2 | 1 | 3 (27.27) | 8 (72.73) | 0.36 | 6 | 1 | 0 | 1 (14.29) | 6 (85.71) | 0.14 |
| CD68 | 0 | 5 | 6 | 11 (100) | 0 (0) | 1.55 | 0 | 3 | 4 | 7 (100) | 0 (0) | 1.57 |
| CD20 | 2 | 6 | 3 | 9 (81.82) | 2 (18.18) | 1.09 | 2 | 5 | 0 | 5 (71.43) | 2 (28.57) | 0.71 |
| PD-L1 | NA | NA | NA | 2 (18.18) | 9 (81.82) | NA | NA | NA | NA | 1 (14.29) | 6 (85.71) | NA |
Cases with more than 1% of positive staining were considered to be positive. Avg. Score is the average score value in each subgroup for each marker. Score 0 < 1%, Score 1 ≥ 1%; <10%, Score 2 ≥ 10%. NA stands for “Not Available”.