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. 2022 Mar 16;23(6):3209. doi: 10.3390/ijms23063209

Table 3.

Antibacterial photodynamic therapy in combination with photothermal hyperthermia therapy.

Photosensitizer and Nanoconjugate System Used Photothermal Therapy Agent Used Gram
Negative
Gram
Positive
Study Phase Impact/Target Ref
Toluidine blue and withindocyanine green indocyanine green S. mutans in vitro biofilm + planktonic/enhanced efficacy [73]
indocyanine
green loaded SPIONs
superparamagnetic iron oxide nanoparticles E. coli,
K. pneumoniae,
P. aeruginosa,
S. epidermis in vitro biofilm + planktonic/synergistic [26]
indocyanine green loaded mesoporous nanoparticles mesoporous polydopamine nanoparticles E. coli,
K. pneumoniae,
P. aeruginosa
S. aureus in vitro biofilm + planktonic/synergistic [114]
toluidine blue coated gold nanorods gold nanorods MRSA in vitro biofilm + planktonic/synergistic [117]
black phosphorus nanosheets conjugated gold nanoparticles BP@AuNP BP@AuNP E. coli S. aureus in vitro
in vivo
biofilm + planktonic/synergistic [118]