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. 2022 Mar 16;23(6):3209. doi: 10.3390/ijms23063209

Table 7.

Combination of antibacterial photodynamic therapy with sonodynamic therapy.

Photosensitizer and Nanoconjugate System Used Sonodynamic Therapy Gram
Positive
Study Phase Impact/Target Ref
uroporphyrin and coproporphyrin III home-made light source/ultrasound generator S. aureus in vitro planktonic, biofilm, no difference between aPDT and SDT [150]
Fe2+ and protoporphyrin IX
conjugated mesoporous
silica nanoparticles
home-made light source/ultrasound generator E. faecalis in vitro planktonic, biofilm, no difference between aPDT and SDT [152]
chlorin e6 derivative Photodithazine® rose bengal Sonidel SP100 sonoporator (sonar 1 MHz and pulse repetition frequency
of 100 Hz
C. albicans in vitro planktonic, biofilm, logCFU/mL reduction: aPDT/SDT: 2.08/3.39, PDT/SDT: eradication [153]