Table 1.
The median and range of IL-31 expression in serum and IL-31, IL-31 RA and OSMR HSCORE levels in the epidermis and dermis of CTCL, AD and CG
| Skin expression, H score median (range) | CTCL | CTCL early stage | CTCL advanced stage | AD | CG | |
|---|---|---|---|---|---|---|
| IL-31 | Epidermis | 200 (100–300) | 200 (100–300) | 200 (100–300) | 100 (100–200) | 100 |
| Dermis | 115 (35–280) | 130 (45–200) | 110 (35–280) | 85 (10–165) | * | |
| IL-31RA | Epidermis | 100 (100–200) | 200 (100–200) | 100 (100–200) | 150 (100–200) | 100 |
| Dermis | 100 (20–280) | 130 (30–215) | 80 (20–280) | 162 (40–200) | * | |
| OSMR | Epidermis | 100 (100–200) | 100 (100–200) | 100 (100–200) | 100 (100–200) | 100 |
| Dermis | 100 (5–200) | 100 (50–195) | 100 (5–200) | 95 (30–215) | * | |
| IL-31 serum expression, median (range) [pg/ml] | 4.82 (2.89–7.74) | 4.89 (3.34–7.74) | 4.62 (2.89–6.27) | 6.09 (4.27–17.48) | 0.00 (0.00–2.73) | |
CTCL – cutaneous T-cell lymphomas, AD – atopic dermatitis, CG – healthy control group, *dermis was not examined in the healthy control group due to lack of inflammatory infiltrate.