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. 2022 Mar 15;15(3):357. doi: 10.3390/ph15030357

Figure 6.

Figure 6

Representative photomicrographs using H&E staining of histological sections for intestines (A–D), and livers (E–H) of rats treated with CIP–MSN compared with CIP alone at 14 days postinfection with S. typhimurium. PC (positive control): rats received a control diet without any addition and were orally challenged with S. typhimurium; MSN(mesoporous silica particles): rats received a control diet, were orally challenged with S. typhimurium, and received 10 mg/kg MSN orally twice a day for 3 days; CIP(ciprofloxacin): rats received a control diet, were orally challenged with S. typhimurium, and received 10 mg/kg CIP orally twice a day for 3 days; and CIP–MSN (MSN particles loaded with ciprofloxacin): rats received a control diet, were orally challenged with S. typhimurium, and received 5 mg/kg CIP orally twice a day for 3 days.