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. 1999 Nov;43(11):2663–2670. doi: 10.1128/aac.43.11.2663

TABLE 1.

Strains tested in this study and their previously publisheda resistance mechanisms

Patient Isolate Efflux pumpb expression level ERG11 point mutation(s)
I C23 S405F heterozygote
I C32 No increase relative to C23 No data
I C39 Increased CDR1 and CDR2 signals relative to C23 S405F homozygote
II C45
II C18 No increase relative to C45
II C46 No increase relative to C45
III C33
III C34 No increase relative to C33 S405F homozygote
III C26 Increased CDR1 and CDR2 signals relative to C33 S405F and Y132H homozygote
III C82 Less pronounced increase in CDR1 and CDR2 signals relative to C33 S405F homozygote
IV C27
IV C37 No increase relative to C27 G464S and R467K homozygote
IV C40 Increased CaMDR1 signal relative to C27 G464S and R467K homozygote, Y132H heterozygote
V C43 G129A heterozygote
V C48 Increased CDR1 and CDR2 signals relative to C43 No data
V C56 Increased CDR1 and CDR2 signals relative to C43 G129A and G464S homozygote
a

References 27 and 29 to 31

b

CDR1, CDR2, and CaMDR1