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IC50s of inhibitors for TEM-type and IRT-type β-lactamases
| Strain (enzyme) | IC50 (μM)
|
|
|---|---|---|
| Clavulanate | Tazobactam | |
| CF19 (TEM-1) | 0.18 | 0.05 |
| CF29 (TEM-2) | 0.09 | 0.04 |
| CF579 (TEM-57) | NDa | ND |
| CF739 (TEM-73 [IRT-18]) | 31 | 12 |
| CF749 (TEM-74 [IRT-19]) | 9.4 | 2.9 |
| CF449 (TEM-44 [IRT-13]) | 10 | 3.0 |
| CF65a [TEM-65 [IRT-16]) | 9.0 | 3.0 |
ND, not done.
