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. 2022 Mar 19;11(6):1713. doi: 10.3390/jcm11061713

Table 6.

Results of selected parameters in HIV-infected men after cART in the subgroup with protease inhibitors (PIs) treatment and the subgroup with integrase transfer inhibitors (INSTIs) treatment with statistical analysis.

Parameters PIs
(N = 25)
INSTIs
(N = 28)
p *
Me (IQR) Me (IQR)
HIV-Infected Men after cART (B)
IRS
[ng/mL]
2.90 (2.30–15.90) 10.60 (2.90–77.40) 0.18
MSTN
[ng/mL]
160.00 (105.20–917.90) 484.70 (110.60–3589.00) 0.20
PYY
[pg/mL]
54.50 (32.60–205.50) 201.20 (30.10–666.60) 0.08
GLP-1
[ng/mL]
159.30 (124.30–709.20) 661.80 (150.00–3484.00) 0.09
DPP-4
[ng/mL]
70.90 (48.30–541.80) 395.80 (52.60–1452.00) 0.14
FETU-A
[ng/mL]
224.25 (142.80–1433.00) 1267.00 (173.50–5173.00) 0.33
PTX3
[ng/mL]
1.95 (1.20–9.80) 8.10 (1.50–43.70) 0.31
SDF-1
[ng/mL]
1.15 (0.70–5.20) 5.20 (0.80–41.10) 0.22
RANTES
[ng/mL]
240.40 (155.40–999.10) 893.90 (169.30–4804.00) 0.24

Abbreviation: cART—combined antiretroviral therapy; B—HIV-infected man after cART; PIs—protease inhibitors treatment; INSTIs—integrase transfer inhibitors; Me—median; IQR—interquartile range; N—number of participants; NS—not statistically significant; IRS—irisin; MSTN—myostatin; PYY—peptide YY; GLP-1—glucagon-like peptide-1; DPP-4—dipeptidyl peptidase IV; FETU-A—fetuin A; PTX 3—pentraxin 3; SDF-1—chemokine stromal cell-derived factor 1; and RANTES—regulated activation normal T cell expressed and secreted. * p—statistical significance by Wilcoxon test.