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Drugs useful and to be avoided in patients with IGEs
| Broad-spectrum ASMs useful in IGEs | Narrow-spectrum ASMs to be avoided in IGEs |
|---|---|
| Valproate | Carbamazepine |
| Lamotrigine (can worsen myoclonus) | Oxcarbazepine |
| Levetiracetam/Brivaracetam | Phenytoin |
| Topiramate | Gabapentin/Pregabalin |
| Zonisamide | Vigabatrin |
| Clobazam | |
| Perampanel | |
| Phenobarbitone |
ASMs: antiseizure medicines; IGEs: idiopathic generalized epilepsies
