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Choice of ASMs based on comorbidities and side benefits of medicines
| Comorbidity | Preferred ASM | Drug (s) to be avoided |
|---|---|---|
| Obesity | Topiramate | Valproate |
| Zonisamide | ||
| Depression | Lamotrigine | Levetiracetam |
| Valproate | ||
| Cognitive dysfunction | Lamotrigine | Topiramate |
| Levetiracetam | Zonisamide | |
| Valproate | ||
| Migraine | Valproate | NA |
| Topiramate | ||
| Lamotrigine | ||
| Neuropathic pain | Lamotrigine | NA |
ASM: Antiseizure medicine
