Table 2.
Role of microRNAs in atherosclerosis initiation and progression.
| Cell Line | Athero-Protective | Pro-Atherogenic |
|---|---|---|
| Endothelial cells | miR-155 [270] miR-10a [271], miR-31 and miR-17-3p [272] miR-146a [275] miR-181b [274] miR-92a [278,279] miR-let-7g [280] |
miR-216a [281] |
| Macrophages | miR-146a [275] miR-125a [276] miR-223 [277] |
miR-125b [282] miR-342-p [283] miR-33 [292] |
| VSMCs * | miR-21 [285] miR-221 and miR-222 [286] miR-26a [287] miR-663 [290] |
miR-143, miR-145 and miR-1 [288] miR-29a and miR-24 [289] miR-133a [288] miR-15b and miR-16 [291] |
* Anti-atherogenic, considered as VSMC activation and phenotype switching.