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. 2022 Mar 8;27(6):1762. doi: 10.3390/molecules27061762

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Relationships between drug-resistance-related proteins and overall survival (OS) in breast cancer patients. The log-rank test of overall survival rate of 194 upregulated proteins (a) and 294 downregulated proteins (b) in TCGA-BRCA pan-cancer (x-axis) and Metabric cohorts (y-axis). The highly significant log-rank p-value in both cohorts was indicated with red (a) and blue (b). Log-rank analysis of overall survival according to expression level of PLXNB2 (c) and ACOX3 (d) in patients treated with chemotherapy from Metabric.