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. 2022 Mar 11;23(6):3053. doi: 10.3390/ijms23063053
AMPAR alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor
AChE acetylcholinesterase
AO adverse outcome
AOP adverse outcome pathway
AUC area under the ROC curve
AUR-TPO Amplex UltraRed-thyroperoxidase
BA balanced accuracy
BRF balanced random forest
CAR constitutive androstane receptor
CYP2E1 cytochrome P450 2E1
DNT developmental neurotoxicity
FN false negative
FP false positive
GABAR GABA receptor
IATA integrated approaches to testing and assessment
KA kainite receptor
KE key event
k-NN k-nearest neighbors
MCC Matthew’s correlation coefficient
MIE molecular initiating event
NADHOX NADH-quinone oxidoreductase
NIS Na+/I symporter
ND neurodegenerative disease
NNET neural networks
NMDAR N-methyl-D-aspartate receptor
OATP1C1 solute carrier organic anion transporter family member 1C14
PCB polychlorinated biphenyls
PXR pregnane X receptor
QSAR quantitative structure-activity relationship
RF random forest
ROS reactive oxygen species
RyR ryanodine-sensitive Ca2+ channel
SEN sensitivity
SPE specificity
THRα thyroid hormone receptor α
THRβ thyroid hormone receptor β
TN true negative
TP true positive
TPO thyroperoxidase
TTR transtyretrin serum binding protein
VGSC voltage-gated sodium channel