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. 2022 Feb 23;10(3):345. doi: 10.3390/vaccines10030345

Table 3.

Bivariate and multivariate analysis for factors associated to ARs after vaccination against SARS-CoV-2 (first dose and second dose).

Dose Any Sign or Symptom Any Local Sign or Symptom Any Systemic Sign or Symptom
cOR 95% CI aOR 95% CI cOR 95% CI aOR 95% CI cOR 95% CI aOR 95% CI
First Female (vs. Male) 1.57 0.99–2.49 - - 1.55 0.98–2.47 - - 1.99 1.11–3.57 - -
Age 31–45 (vs. > 45 years) 1.81 1.02–3.22 - - 1.53 0.86–2.71 - - 1.82 0.90–3.70 - -
Age < 31 (vs. > 45 years) 2.66 1.5–4.7 - - 2.66 1.50–4.71 - - 1.66 0.82–3.35 - -
Healthcare worker (vs. No Healthcare worker) 1.41 0.85–2.35 - - 1.32 0.80–2.20 - - 0.96 0.52–1.76 - -
Distance between the first and the second dose (for day increase) 1.16 0.70–1.90 - - 1.14 0.70–1.88 - - 0.99 0.54–1.80 - -
Second Female (vs. Male) 2.09 1.16–3.76 1.81 0.97–3.35 1.81 1.06–3.09 1.57 0.90–2.74 1.96 1.18–3.26 1.79 1.06–3.02
Age 31–45 (vs. > 45 years) 2.15 1.11–4.15 1.92 0.98–3.78 2.15 1.15–4.01 1.98 1.05–3.73 1.68 0.93–3.05 1.51 0.82–2.76
Age < 31 (vs. > 45 years) 8.07 3.20–20.32 7.47 2.95–18.91 4.89 2.37–10.08 4.59 2.21–9.52 3.54 1.84–6.81 3.27 1.68–6.34
Healthcare worker (vs. No Healthcare worker) 1.25 0.67–2.31 - - 1.05 0.59–1.87 - - 1.06 0.61–1.84 - -
Distance between the first and the second dose (for day increase) 1.34 0.73–2.45 - - 1.39 0.80–2.42 - - 1.35 0.80–2.29 - -

cOR = crude Odds ratio. aOR = Adjusted Odds Ratio.