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. 2022 Mar 11;23(6):3018. doi: 10.3390/ijms23063018
CRP C-reactive protein
IL interleukin
TNF tumor necrosis factor
CGRP calcitonin gene-related peptide
MO migraine without aura
SP substance P
MZ monozygotic twins
DZ dizygotic twins
HIS International Headache Society
GWAS genome-wide association studies
FHM familial hemiplegics
ATP adenosine triphosphate
CACNA1A calcium voltage-gated channel subunit alpha1 A
GWA genome-wide association meta-analysis
SNP single nucleotide polymorphism loci
WGHS Women’s Genome Health Study
FGF6 fibroblast growth factor 6
HPSE2 heparanase 2
NPFF neuropeptide precursor of the FF-amide peptide
ASIC acid-sensitive ion channels
CSD cortical diffusion depression
NSAIDs nonsteroidal anti-inflammatory drugs
DHE dihydroergotamine
5-HT 5-hydroxytryptamine
NF-κB nuclear factor kappa-light-chain-enhancer
SNAP synaptosomal-associated protein
ACE angiotensin-converting enzyme inhibitors
ARB angiotensin receptor blocker
MTHFR methylenetetrahydrofolate reductase
MTRR methionine synthase reductase
CoQ10 coenzyme Q10
NMDA N-methyl-D-aspartate
MMD migraine days monthly
CGRP calcitonin gene-related peptide
CNS central nervous system
PNS peripheral nervous systems
LC locus coeruleus
PAG periaqueductal grey matter
VIP vasoactive intestinal polypeptide
VPAC1 and VPAC2 vasoactive intestinal polypeptide receptors 1 and 2
PACAP pituitary adenylate cyclase-activating polypeptide
SPG parasympathetic sphenopalatine ganglia
MCAs middle cerebral arteries
MMAs middle meningeal arteries
NPY neuropeptide Y
TRIG trigeminal ganglia