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Composition, experimental, and Design Expert® predicted values of the optimal BER-CTS-NLCs formulation.
| Independent Factors | Optimal Value | Response | ExperimentalValue | Design Expert® Predicted Value | Prediction Error (%) * |
|---|---|---|---|---|---|
| X1: GMS amount (mg) | 114.7 | PS (nm) | 142.1 ± 5.7 | 119.8 | 15.7 |
| X2: Poloxamer 407 (% w/w) | 1.8 | EE% | 80.3 ± 3.1 | 76.1 | 5.2 |
| X3: Oleic acid amount (mg) | 30 | CDR% | 85.6 ± 4.2 | 88.2 | 3 |
* Calculated as (Experimental value-Design Expert® predicted value)/Experimental value × 100.
