Table 3.
Natural compounds as antiquorum sensing molecules in biofilm dispersal.
Compound/Molecule | Mode of Action | Effective Against | Reference |
---|---|---|---|
Garlic extracts | inhibits QS | P. aeruginosa | [62] |
Garlic extracts | inhibit LasR and LuxR | P. aeruginosa | [63] |
Isolimonic acid | cell-cell signaling | E. coli | [64,65] |
Isolimonic acid | reduce LuxR DNA binding | Vibrio spp. | [65] |
Cinnamaldehyde | swimming motility | E. coli | [66] |
Hordenine | decrease in signaling molecule, inhibition of QS-related genes | P. aeruginosa | [67,68] |
Autoinducing peptide type I (AIP-I) | inhibit QS | S. aureus | [74] |
RNAIII-inhibiting peptide (RIP) | inhibit QS | S. aureus | [75] |
Querentin | decrease LasI/R, RhlI/R expressions | P. aeruginosa | [73] |