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. 2022 Feb 25;11(3):292. doi: 10.3390/pathogens11030292

Table 3.

Natural compounds as antiquorum sensing molecules in biofilm dispersal.

Compound/Molecule Mode of Action Effective Against Reference
Garlic extracts inhibits QS P. aeruginosa [62]
Garlic extracts inhibit LasR and LuxR P. aeruginosa [63]
Isolimonic acid cell-cell signaling E. coli [64,65]
Isolimonic acid reduce LuxR DNA binding Vibrio spp. [65]
Cinnamaldehyde swimming motility E. coli [66]
Hordenine decrease in signaling molecule, inhibition of QS-related genes P. aeruginosa [67,68]
Autoinducing peptide type I (AIP-I) inhibit QS S. aureus [74]
RNAIII-inhibiting peptide (RIP) inhibit QS S. aureus [75]
Querentin decrease LasI/R, RhlI/R expressions P. aeruginosa [73]