Table 2.
Patients’ baseline characteristics depending on vitamin D status.
| Parameters | Vitamin D Status | p | |
|---|---|---|---|
| Normal (n = 69) | Deficiency/Insufficiency (n = 242) |
||
| Age, years, Me + IQR [25; 75] | 58 [48; 69] | 64 [55; 72] | 0.002 |
| Gender, female, n (%) | 37 (53.6) | 120 (49.6) | 0.550 |
| Disease severity, n (%) | |||
| Mild Moderate Severe |
7 (10.2) 56 (81.1) 6 (8.7) |
3 (1.3) 117 (48.3) 122 (50.4) |
< 0.001 |
| Vitamin D status, n (%) | |||
| Normal Insufficiency Deficiency Severe deficiency |
69 (100) - - - |
- 58 (23.9) 184 (76) 102 (42.1) |
|
| Days from symptom onset to hospitalization, days, Me + IQR [25; 75] | 7 [4; 10] | 8 [6; 11] | 0.050 |
| Bed days, days, Me + IQR [25; 75] | 14 [9; 19] | 17 [13; 23] | 0.002 |
| ICU, n (%) | 9 (13) | 97 (40,1) | 0.001 |
| Discharge, n (%) | 66 (95.6) | 191 (78.9) | 0.001 |
| CT lung involvement, %, Me + IQR [25; 75] | 15 [5; 25] | 48 [35; 70] | <0.001 |
| CT grading, n (%) | |||
| 1 2 3 |
39 (56.5) 16 (23.2) 1 (1.4) |
24 (9.9) 107 (44.2) 64 (26.4) |
<0.001 |
| BMI, kg/m2, Me + IQR [25; 75] | 28 [25; 32] | 30 [26; 33] | 0.13 |
| Obesity, n (%) | 22 (31.8) | 103 (42.6) | 0.27 |
| DM type 2, n (%) | 22 (31.8) | 82 (33.8) | 0.70 |
| AH, n (%) | 48 (69.6) | 192 (79.3) | 0.08 |
| IHD, n (%) | 19 (27.5) | 87 (35.9) | 0.19 |
| CKD, n (%) | 5 (7.2) | 29 (11.9) | 0.26 |
| 25(OH)D, ng/mL, Me + IQR [25; 75] | 36.1 [32.7; 38.0] | 13.7 [8.2; 19.3] | <0.001 |
| Neutrophils, ×109/L, Me + IQR [25; 75] | 4.8 [3.1; 6.5] | 5.3 [3.4; 7.8] | 0.12 |
| Lymphocytes, ×109/L, Me + IQR [25; 75] | 1.2 [0.8; 1.5] | 1.0 [0.8; 1.4] | 0.08 |
| NLR, Me + IQR [25; 75] | 4.1 [2.4; 6.8] | 5.2 [2.8; 9.1] | 0.03 |
| Plasma glucose, mmol/L, Me + IQR [25; 75] | 6.6 [5.7; 8.2] | 7.0 [6.1; 8.6] | 0.04 |
| CRP, mg/L, Me + IQR [25; 75] | 28.3 [7.6; 62.5] | 79.7 [32.5; 146.7] | <0.001 |
| Ferritin, ng/mL, Me + IQR [25; 75] | 411 [183; 786] | 627 [289; 1155] | 0.002 |
| LDH, u/L, Me + IQR [25; 75] | 331 [239; 455] | 449 [316; 609] | <0.001 |
| D-dimer, µg/mL FEU, Me + IQR [25; 75] | 0.3 [0.2; 0.4] | 0.4 [0.3; 0.7] | 0.002 |
| Creatinine, µmol/L, Me + IQR [25; 75] | 71 [60.5; 82.5] | 65 [55; 79] | 0.043 |
ICU—intensive care unit; BMI—body mass index; DM—diabetes mellitus; AH—arterial hypertension; IHD—ischemic heart disease; CKD—chronic kidney disease; NLR—neutrophils/lymphocytes ratio; 25(OH)D—25-hydroxyvitamin D; CRP—C-reactive protein; LDH—lactate dehydrogenase; Me—median; and IQR—interquartile range.