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Weight and thickness of mucoadhesive estradiol buccal films (3.2 cm × 2.2 cm) prepared by co-solvency and nano-emulsion approach (n = 3).
| Film Preparation Approach | Weight (mg) | Thickness (mm) | ||
|---|---|---|---|---|
| Mean ± SD | p-Value | Mean ± SD | p-Value | |
| Co-solvency | 0.102 ± 0.004 | <0.001 | 0.14 ± 0.01 | 0.492 |
| Nano-emulsion | 0.133 ± 0.00 | 0.15 ± 0.01 | ||
