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. 2022 Mar 15;13(3):517. doi: 10.3390/genes13030517

Table 2.

Specificity, sensitivity, positive and negative predictive value, and detection rate at different Phe cut-offs.

Number of newborns 37,784
Phe cut-off value (µmol/L) 120 130 140 150 160 170 180 190 200
Recalls (N) 108 41 21 16 12 11 11 9 9
False positive (N) 102 35 15 10 6 5 5 3 3
True positive (N) 6 6 6 6 6 6 6 6 6
False negative (N) 0 0 0 0 0 0 0 0 0
True negative (N) 37,676 37,743 37,763 37,768 37,772 37,773 37,773 37,775 37,775
Detection rate (%) 0.019 0.019 0.019 0.019 0.019 0.019 0.019 0.019 0.019
Sensitivity (%) 100 100 100 100 100 100 100 100 100
Specificity (%) 99.73 99.91 99.96 99.97 99.98 99.99 99.99 99.99 99.99
Positive predictive value (%) 5.56 14.63 28.57 37.50 50.00 54.55 54.55 66.67 66.67
Negative predictive value (%) 100 100 100 100 100 100 100 100 100