Figure 12.
DNA oxidative damage in colonic mucosa of a normal diet (ND) or a high fat diet (HFD) mice with or without TNBS colitis subjected to exercise on spinning wheels (SW) or the intestinal alkaline phosphatase (IAP) treatment alone or the combination of SW and IAP. Results are mean ± S.E.M. of 6–8 animals per group. An asterisk indicates a significant change (p < 0.05) as compared to the respective values in the control mice fed an ND. An asterisk with cross indicates a significant change (p < 0.05) as compared to the respective values in the sedentary mice (SEDEN) with TNBS-induced colitis fed a HFD. A cross indicates a significant change (p < 0.05) as compared to the respective values in the HFD fed colitis mice with access to SW.