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. 2022 Mar 9;23(6):2964. doi: 10.3390/ijms23062964

Figure 13.

Figure 13

Plasma level of interleukin-2 (IL-2), IL-6, IL-10, IL-12p70, IL-17a, tumor necrosis factor-alpha (TNF-α), monocyte chemoattractant protein-1 (MCP-1) and leptin in mice fed a normal diet (ND) or a high fat diet (HFD) with experimental TNBS colitis exercising on spinning wheels (SW) and administered with IAP alone or combined with SW. Results are mean ± S.E.M. of 6–8 animals per group. An asterisk indicates a significant change as compared to the respective values in the sedentary mice fed ND for IL-2 and IL-6, as compared to the respective values in the sedentary mice fed HFD for IL-10, IL-17a, TNF-α, MCP-1 and leptin, and as compared to the respective values in the sedentary mice fed HFD with TNBS colitis for IL-12p70. An asterisk with a cross indicates a significant change (p < 0.05) as compared to the respective values in the sedentary mice fed a HFD for IL-2 and IL-6, as compared to the respective values in the sedentary mice fed HFD with TNBS colitis for IL-10, IL-17a, TNF-α, MCP-1 and leptin, and as compared to the respective values in the mice fed HFD access to SE and TNBS colitis for IL-12p70. A cross indicates a significant change (p < 0.05) as compared to the respective values in the sedentary mice fed HFD with TNBS colitis for IL-2 and IL-6, as compared to the respective values in the sedentary mice fed HFD with access to SW and TNBS colitis for IL-10, IL-17a, TNF-α and leptin. A hash indicates a significant change (p < 0.05) as compared to the respective values in the obese animals exercising on a spinning wheel with colitis for IL-2 and IL-6.