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. 2022 Mar 10;23(6):2977. doi: 10.3390/ijms23062977

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Reactivity against peptide candidates from SARS-CoV-2 and HCoV-OC43 N proteins in pre-COVID-19 cohort determined by ELISA assays. (a) Heatmap with OD450nm readings for each sample. Cutoff for negative binding was established at OD450 = 0.2. (b) Frequency of cross-reacting serum samples among all tested serum samples in the pre-COVID-19 cohort.