Table 1.
Characteristics, outcome measures, and quality ratings of included studies.
| Study | Publication Year | Sample Size (CPR/eCPR) | Location | Study Design | ECMO Cannulation Location a | Primary Outcome | Secondary Outcome(s) | Study Quality Rating |
|---|---|---|---|---|---|---|---|---|
| Bougouin et al. [21] | 2020 | 12,666/525 | France | Retrospective, Obs | - | Survival to hospital discharge | CPC 1 or 2 at hospital discharge | 8 |
| Choi et al. [22] | 2016 | 50/10 | Korea | Retrospective, Obs | - | CPC 1 or 2 at 1 month | Survival at 1 month | 7 |
| Choi et al. [23] | 2016 | 320/320 | Korea | Retrospective, Obs | - | CPC 1 or 2 at hospital discharge | Survival to hospital discharge | 8 |
| Kim et al. [24] | 2014 | 52/52 | Korea | Retrospective, Obs | ED, Cath Lab | CPC 1 or 2 at 3 months | Survival at 24 h, hospital discharge, and 3 months | 8 |
| Kitada et al. [25] | 2020 | 2278/307 | Japan | Retrospective, Obs | - | CPC 1 or 2 at 1 month | None | 9 |
| Maekawa et al. [26] | 2013 | 24/24 | Japan | Retrospective, Obs | - | CPC 1 or 2 at 3 months | None | 9 |
| Nakashima et al. [27] | 2019 | 157/250 | Japan | Retrospective, Obs | - | CPC 1 or 2 at 6 months | Survival at 6 months | 9 |
| Patricio et al. [28] | 2019 | 50/49 | Belgium | Retrospective, Obs | - | CPC 1 or 2 at 3 months; survival to ICU discharge * | None | 8 |
| Sakamoto et al. [20] | 2014 | 194/260 | Japan | Prospective, Obs | - | CPC 1 or 2 at 1 and 6 months | None | 7 |
| Schober et al. [29] | 2017 | 232/7 | Austria | Retrospective | ED | CPC 1 or 2 at 6 months | None | 8 |
| Yannopoulos et al. [19] | 2017 | 170/62 | USA | Prospective | Cath Lab | CPC 1 or 2 at discharge | CPC 1 or 2 at 3 months | 7 |
| Yannopoulos et al. [7] | 2020 | 15/15 | USA | RCT | Cath Lab | Survival to hospital discharge | Survival at 1, 3, and 6 months; CPC 1 or 2 at hospital discharge, 1, 3, 6 months | Low risk |
| Yoshida et al. [30] | 2020 | 493/38 | Japan | Retrospective | - | CPC 1 or 2 at 1, 3 months | Survival at 1, 3 months | 7 |
a (-): Data not reported. * Both listed as primary outcome. Abbreviations: CPR, cardiopulmonary resuscitation; ECPR, extracorporeal cardiopulmonary resuscitation; ECMO, extracorporeal membrane oxygenation; Obs, observational; USA, United States of America; RCT, randomized controlled trial; ED, Emergency Department; Cath Lab, cardiac catheterization laboratory.