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. 2022 Mar 17;23(6):3242. doi: 10.3390/ijms23063242

Table 2.

Cytological diagnoses of secondary thyroid cancers by fine needle aspiration.

Author (Year) No. of FNAs Performed on STCs Proportion of STCs Diagnosed Correctly as Metastasis on FNA Proportion of STCs Diagnosed as Suspicious for Malignancy/Unknown Primary on FNA Proportion of STCs with Other Diagnoses on FNA
HooKim et al. (2015) 28 85.7% 14.3% 0%
Hegerova et al. (2015) 97 94% 0% 6% follicular neoplasm or papillary thyroid carcinoma
Pusztaszeri et al. 2015 62 81% 0% 8% nondiagnostic
5% follicular neoplasm
7% primary thyroid cancer
Choi et al. (2016) 41 46.3% 24.4% 4.9% benign
9.8% nondiagnostic
4.9% atypia or follicular lesion of undetermined significance
9.8% others
Straccia et al. (2017)–meta-analysis 154 72.7% 26.6% 0.65% primary thyroid cancer
Zivaljevic et al. (2018) 6 33% Nil data provided Nil data provided
Stergianos et al. (2021) 29 41.4% Nil data provided 0.07% follicular neoplasm
0.03% benign
0.03% papillary thyroid cancer
0.03% anaplastic thyroid cancer

FNA, fine-needle aspiration; STC, secondary thyroid cancer.