Figure 1.

Figure 1 shows the protocol. After randomisation, 1/3 was a watchful waiting control group, and 2/3 of patients were placed on an open label low-FODMAP diet and provoked double-blinded with placebo and FODMAPs, respectively in a cross-over fashion. Between provocations there was a two-week low-FODMAP diet wash out. During the study, patients had three identical consultations with questionnaires, blood and stool sampling. A symptom diary was filled in daily throughout the entire study period.