Table 2.
Baseline participant demographics.
| Demographics | Control Group | Low FODMAP Diet |
|---|---|---|
| n | 7 | 12 |
| m/w | 0/7 | 2/10 |
| Age (median (IQR)) | 47 (42; 48) | 38 (32; 50) |
| Caucasian | 7/7 | 12/12 |
| Weight (median (IQR)) kg | 85.0 (54.2; 93.7) | 72.4 (64.6; 87.2) |
| Debut year (median (IQR)) | 2010 (2009; 2012) | 2012 (2005; 2016) |
| Family members with CU (%) | 2 (29%) | 3 (25%) |
| Smoker (%) | 2 (29%) | 1 (8.3%) |
| Screening questionnaires | ||
| SCCAI (median (IQR)) | 3 (2; 5) | 4 (3; 5) |
| Endo Mayo score (median (IQR) | 1 (1; 1) | 1 (1; 2) |
| Missing (no endoscopy?) | 2 | 3 |
| Treatment | ||
| 5-ASA treatment (%) | 3 (43%) | 5 (42%) |
| Azathioprine (%) | 0 (0.0%) | 1 (8.3%) |
| Biologics (%) | 1 (14%) | 1 (8.3%) |
| Questionnaires at baseline, visits 2 and 3 | ||
| IBS-SSS score (median (IQR)) | 273 (248; 280) | 239 (208; 278) |
| Symptom score (average of 1 week) (median (IQR)) | 34.5 (28.5; 42.7) | 15.8 (11.5; 25.8) |
| Bristol Stool Score (average of 1 week), median (IQR)) | 4.0 (3.1; 5.0) | 5.0 (4.3; 5.2) |
| Stool frequency/day (average of 1 week) | 2.1 (1.6; 2.3) | 1.5 (1.1; 2.5) |
| GSRS score (median (IQR)) | 44 (36; 67) | 45 (36; 50) |
| SF-36 score (median (IQR)) | 75.6 (50.0; 84.7) | 76.1 (52.4; 82.1) |
| HADS score (median (IQR)) | 10 (5; 18) | 9 (4; 14) |
| VSI score (median (IQR)) | 55 (29; 63) | 54 (48; 65) |
| AR (% yes) | 6 (85.7%) | 3 (25.0%) |
| PHQ15 (median (IQR) | 12 (9; 19) | 11 (10; 16) |
| Daily FODMAP intake | ||
| GOS | 0.57 (0.54; 1.19) | 0.73 (0.61; 0.78) |
| Fructans | 4.87 (4.14; 5.57) | 4.67 (3.84;4.80) |
| Fructose | 1.23 (1.14; 2.14) | 3.15 (1.37; 30.83) |
| Lactose | 1.37 (0.70; 5.35) | 10.19 (7.04; 11.64) |
| Sorbitol | 0.36 (0.18; 2.04) | 0.38 (0.14; 1.63) |
| Mannitol | 0.03 (0.01; 0.08) | 0.06 (0.06; 0.11) |
Abbreviations: FODMAPS: Fermentable oligo-; di, and monosaccharides and polyols; n: Number; m: men; w: Women; IQR: Inter-quartile range; UC: Ulcerative colitis; SCCAI: Simple Clinical Colitis Activity Index; 5-ASA: 5-Aminosalicylates; IBS-SSS score: Irritable bowel symptom severity score; GSRS: IBS-specific Gastrointestinal Symptom Rating Scale; SF-36: Short Form 36 Health Survey; HADS: Hospital Anxiety and Depression Scale; VSI: The Visceral Sensitivity Index; AR: Irritable Bowel Syndrome Adequate Relief; PHQ15: Patient Health Questionnaire; GOS; GalactoOligoSaccharide.