Table 2.
Clinicopathological and demographic characterization of breast cancer samples along with expressions of HK2, PKM2, and PFKM.
| Variables | Total (%) | HK2 high | PKM2 high | PFKM high |
|---|---|---|---|---|
| Age of disease onset ≤45 | 30(50) | 19 | 21 | 21 |
| Age of disease onset >45 | 30(50) | 22 | 23 | 27 |
| Premenopausal status | 25(42) | 14 | 20 | 17 |
| Postmenopausal status | 35(58) | 27 | 24 | 31 |
| Laterality (left) | 30(50) | 19 | 21 | 23 |
| Laterality (right) | 30(50) | 22 | 23 | 25 |
| Grade I/II | 45(75) | 28 | 32 | 35 |
| Grade III | 15(25) | 13 | 12 | 13 |
| Stage I/II | 41(68) | 26 | 30 | 32 |
| Stage III/IV | 19(22) | 15 | 14 | 16 |
| N0/N1 | 49(82) | 32 | 36 | 38 |
| N2/N3 | 11(18) | 9 | 8 | 10 |
| No metastasis(M0) | 57(95) | 38 | 41 | 45 |
| Distant metastasis(M1) | 3(5) | 3 | 3 | 3 |
| T1/T2 | 40(67) | 28 | 29 | 30 |
| T3/T4 | 20(33) | 13 | 15 | 18 |
N0/N1 = nodes involved ≤ 4; N2/N3 = nodes involved ≥ 4; T1/T2 = size of tumor is ≤5 cm; T3/T4 = size of tumor is ≥5 cm; M0 = cancer not spread to other parts of the body; M1 = cancer spread to other parts; % = percentage.