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. 2022 Mar 7;13(3):468. doi: 10.3390/genes13030468

Figure 1.

Figure 1

Identification of the candidate DEM. The heatmap (A) and volcano plot (B) of miRNAs in GSE87718, the screening threshold are p value < 0.05 and | FC| > 1. The heatmap (C) and volcano plot (D) of miRNAs in GSE143845, the screening threshold are adjusted to p value < 0.01 and |Log FC| > 2. The Venn diagram (E) and FC (GSE87718) and LogFC (GSE143845) heatmap (F) of overlapping DEMs. Abbreviations: DEMs, differentially expressed microRNAs. (G) The expression of miR-185-5p in RAW264.7 macrophages with or without 100 ng/mL LPS for 24 h. Mean ± SD; n = 3; *** p < 0.001.